Botulism
Test	Botulism
Indication	Botulism is a neurotoxin, botulism may be produced by C. botulinum in foods which have been improperly preserved. Food poisoning inlude vomiting and abdominal pain, disturbances of vision, motor function and secretion, mydriasis, ptosis, dry mouth and cough. The test is used to diagnose infant botulism, sudden death syndrome, floppy baby syndrome, classic botulism in adults.
Physiology	Infant botulism causes hypotonia (floppy baby syndrome), constipation, difficulty in feeding, and a weak cry. Some cases of sudden death syndrome has been found due to ingestion of honey containing C. botulinum
Normal Range	No toxin identified, no clostridium botulinum isolated.
Sample	Vomit, serum, stool, gastric washings, cerbrospinal fluid or autopsy tissue, food samples.
Test Method	Toxin neutralization test in mice.
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