Medindia » Blood test »  Hematology Test »  Red Blood Cell Enzyme Deficiency, Quantitative/ Erythrocyte Enzyme Deficiency/ RBC enzymes.
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Red Blood Cell Enzyme Deficiency, Quantitative/ Erythrocyte Enzyme Deficiency/ RBC enzymes.

Lab Test
Test Red Blood Cell Enzyme Deficiency, Quantitative/ Erythrocyte Enzyme Deficiency/ RBC enzymes.
Indication The test is used to investigate hemolytic anemia
Normal Range G-6-PD: 8.6-18.6 IU/g hemoglobin; Phospho-hexoisomerase: 14.7-42.2 IU/g hemoglobin; Pyruvate kinase: 2.0-8.8 IU/g hemoglobin.
Interpretation Individuals with low levels of RBC G6-PD deficiency include: analgesics/antipyretics: aspirin; sulfa drugs: sulfapyridine, sulfa drugs: sulfapyridine, sulfisoxazole; antimalarias: primaquine, pentaquine, quinine; nitrofurantoin; Chloromycetin, quinidine, para-ainosalicyclic acid;others. Deficient or absent RBC enzyme activity may relate to absence of or decreased level of the enzyme, presence of an inactive molecular form or of an isoenzymes with altered activity. Glutathione reductase deficiency also occurred in some cases of malnutrition, liver disease, and sepsis.
Related Tests Auto-hemolysis, Glucose-6-Phosphate Dehydrogenase, Heinz Body Stain, Red Blood Cell Enzyme Deficiency Screen
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Member Comments ( 1 )
Lower values of Iron signifies Iron deificiency anemia & not pernicious anemia. Plaese make a correction in above interpretation.
(Posted by DNA_Diagnostics, India Date : 6/16/2010 )