Blood Test/Hematology Test – APT test/Swallowed Blood syndrome Test/ Fetal hemoglobin

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Medindia » Blood test » Hematology Test » APT test/Swallowed Blood syndrome Test/ Fetal hemoglobin

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Hematology Test

APT test/Swallowed Blood syndrome Test/ Fetal hemoglobin

Test

APT test/Swallowed Blood syndrome Test/ Fetal hemoglobin

Indication

This test is done to diagnose swallowed blood syndrome and differentiate this condition from gastrointestinal hemorrhage in the new born.

Physiology

This test uses alkali denaturation of fetal hemoglobin to determine if blood is present in the stool of a newborn as a result of swallowing maternal blood or is due to perinatal or neonatal Gastro-intestinal hemorrhage. In swallowed blood syndrome, blood or bloody stools are passed usually on the second or third day of life. The blood may be swallowed during delivery or may be from a fissure of the mother’s nipple. The test is based on the fact that the infant’s blood contains > 60% fetal hemoglobin that is alkali resistant. Swallowed blood of maternal origin contains adult hemoglobin, which is converted to brownish alkaline hematin on the addition of alkali.

Normal Range

Report will provide indication if blood is of maternal or infant origin (adult or fetal hemoglobin).

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Member Comments ( 2 )

Mycobacterium Tuberculosis is an aerobic bacteria that is why when a tuberculoma transforms to a cavitatory lesion, the number of bacteria increase to enormus number.If communication between cavity and bronchus is esatablished, then the bacteria coughed out during coughing. Cavitatory pulmonary lesion must be considered sputum +ve until and unless prove otherwise. Always do the microscopy of such patients and even saliva may have bacteria(AFB was detected in saliva of such patient)
(Posted by ANWAR, Pakistan Date : 2/10/2010 )

thank for the information on this web, as i was reading on Apt`s test,I was expecting that you were going to explain more especially in terms of the results after that test has been done, but you didn`t say anything!! how would i know if the blood is the fetal or maternal???
(Posted by Doctor21, South Africa Date : 7/13/2009 )

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