Gene Therapy
 About Gene therapy
 What are the genes?
 How does gene therapy  work?
 Types of gene  therapy
 Viral gene delivery   systems
 Non-viral gene  delivery  systems
 Pro-drug activation  therapy
 Two-gene therapy
 Nucleic acid  therapeutic agents
 Antisense RNA  production
 Antisense  Oligonucleotides
 Nucleic acid  pharmaceuticals
 Ribozymes - as  therapeutic  agents
 Oligonucleotide  correction  of genetic
 History of events - gene  therapy
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Gene Therapy Treatment

History of events - Gene therapy  
  • 1970s: Synthetic and viral vectors can be used to deliver corrected genes into cells.

  • 1972: Gene therapy was first proposed as method of  manipulating cells and cure genetic disease like cystic fibrosis, phenylketonuria and cancers. 

  • 1995: Non viral gene transfer system using cationic liposome/DNA complexes developed.