Gene Therapy
 About Gene therapy
 What are the genes?
 How does gene therapy  work?
 Types of gene  therapy
 Viral gene delivery   systems
 Non-viral gene  delivery  systems
 Pro-drug activation  therapy
 Two-gene therapy
 Nucleic acid  therapeutic agents
 Antisense RNA  production
 Antisense  Oligonucleotides
 Nucleic acid  pharmaceuticals
 Ribozymes - as  therapeutic  agents
 Oligonucleotide  correction  of genetic
 History of events - gene  therapy
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Gene Therapy Introduction

Oligonucleotide correction of Genetic conditions

- Mr.V.G.Prem Kumar 

  
  • Ability to convert a mutant base pair of a gene to the wild type (normal) version would reverse the consequences of  many different genetic conditions.


  • Strategy using modified RNA-DNA oligonucleotides with 68 nucleotides has been devised for this purpose.